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Quickstart

Use this page to check that CBIcall runs on the shipped example data, then run your own YAML file.

If you still need to choose an installation method or workflow, start with the Overview.

1. Confirm the CLI

bin/cbicall --help
bin/cbicall --version

You should see the command help and the installed CBIcall version.

2. Run the WES Example Test

From the repository root:

bin/cbicall test --wes -t 1

This runs the bundled WES example and compares the generated VCF with the shipped reference output.

Need deeper checks?

Use Integration Tests for bundled WES/mtDNA test details, Configuration Reference for validate-param, and Resource Validation for resource catalog checks.

3. Optional: Run the mtDNA Test

Run this after the WES test works:

bin/cbicall test --mit -t 1
Architecture

The mtDNA workflow uses MToolBox and is x86_64-only. If you are on ARM / aarch64, run WES/WGS workflows there but move mtDNA runs to an x86_64 host.

4. Run With Your Own YAML

Once the integration tests work, use the normal invocation:

bin/cbicall run -p parameters.yaml -t 4
OptionMeaning
-pYAML parameters file.
-tThreads passed to the workflow.

For most WES/WGS runs, start with 4 threads and adjust after checking Performance.

Next Steps

GoalPage
Run real WES/WGS dataEnd-to-end Example: WES
Run mtDNA analysisEnd-to-end Example: mtDNA
Check reproducibilityRun Comparison
Understand generated filesOutputs