CBIcall

Configuration-driven variant calling

Define one analysis in YAML. CBIcall validates it, runs the selected workflow through a supported backend, and records the evidence needed to audit and compare runs.

Quick start Overview

Analysis request

mode: single
pipeline: wes
workflow_backend: nextflow
software_stack: gatk-4.6
genome: b37

Workflowresolved

Resourcesverified

Auditenabled

Paired-end FASTQ reads aligned into a BAM pileup and reported as a filtered VCF

FASTQPaired-end reads

BAMAligned read evidence

VCFFiltered variant calls

From paired-end sequencing reads to filtered VCFs with structured audit evidence.

Get started

Install and run

Install from PyPI, Docker, or Apptainer and execute the shipped WES test.

Analyses

Select a pipeline

Review the bundled WES, WGS, and mtDNA workflows for single-sample and cohort analysis.

Reproducibility

Audit independent runs

Compare workflow identity, resources, runtime evidence, and final-output fingerprints.

Developers

CBIcall

Install and run

Select a pipeline

Audit independent runs

Add an implementation